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Death by SARS-CoV 2: a Romanian COVID-19 multi-centre comorbidity study.

University of Medicine and Pharmacy "Carol Davila", 37 Dionisie Lupu Str., 020021, Bucharest, Romania. National Institute of Diabetes, Nutrition and Metabolic Diseases "N. C. Paulescu", 5-7. Ion Movila Str, 030167, Bucharest, Romania. Department of Applied Mathematics, University POLITEHNICA of Bucharest, Splaiul Independentei 313, 060042, Bucharest, Romania. Mihaela.Pricop@upb.ro. Center for Research and Training in Innovative Techniques of Applied Mathematics in Engineering-Traian Lalescu-(CiTi), University Politehnica of Bucharest, Splaiul Independentei 313, 060042, Bucharest, Romania. Mihaela.Pricop@upb.ro. Center for Health Outcomes & Evaluation, Splaiul Unirii 45, 030126, Bucharest, Romania. Center for Innovation in Medicine, Bd. Theodor Pallady, No. 42J, Room 1719, 032266, Bucharest, Romania. Department of Internal Medicine, Faculty of Medicine, Ovidius University of Constanta, University C2 Street, 900527, Constanţa, Romania. Victor Babes" University of Medicine and Pharmacy, 2 Eftimie Murgu, 300041, Timisoara, Romania. Center for Research and Training in Innovative Techniques of Applied Mathematics in Engineering-Traian Lalescu-(CiTi), University Politehnica of Bucharest, Splaiul Independentei 313, 060042, Bucharest, Romania. Department of Mathematical Methods and Models, University POLITEHNICA of Bucharest, Splaiul Independentei 313, 060042, Bucharest, Romania. Prof. Dr. D. Hociota" Institute of Phonoaudiology and Functional ENT Surgery, 21st Mihail Cioranu Street, 061344, Bucharest, Romania. IRCCS MultiMedica, 300 Milanese Str, 20099, Milan, Sesto San Giovanni, Italy. Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of South Carolina, 6311 Garners Ferry Rd, Columbia, SC, 29209, USA. Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 61 Piazza Marina Str, 90133, Palermo, Italy.

Scientific reports. 2020;(1):21613
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Abstract

Evidence regarding the relation between SARS-CoV-2 mortality and the underlying medical condition is scarce. We conducted an observational, retrospective study based on Romanian official data about location, age, gender and comorbidities for COVID-19 fatalities. Our findings indicate that males, hypertension, diabetes, obesity and chronic kidney disease were most frequent in the COVID-19 fatalities, that the burden of disease was low, and that the prognosis for 1-year survival probability was high in the sample. Evidence shows that age-dependent pairs of comorbidities could be a negative prognosis factor for the severity of disease for the SARS-CoV 2 infection.

Methodological quality

Publication Type : Clinical Trial ; Multicenter Study

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